MyBioSource.com's RABBIT ANTI PPAR DELTA (N-TERMINAL) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The RABBIT ANTI PPAR DELTA (N-TERMINAL) Antibody was generated using NUC1, PPAR-beta, and Ppard as the antigen and it reacts with Mouse, Rat, Non-Human Primate, and Rabbit.
Description
MBS221543 detects peroxisome proliferator-activated receptor, delta (PPARD), a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis